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Chronic granulomatous disease (CGD) is a rare group of hereditary disorders which impair certain cells of the immune system

We reasoned that this approach would reveal synthetic lethal interactions, i wi mit mit.edu) References 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26

They then shifted their focus toward mitochondrial membrane proteins, screening for transporters that stood out as essential for metastatic cells growing in the lung