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Glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy) and dual GIP/GLP-1 receptor agonists like tirzepatide (Mounjaro, Zepbound) are injectable medications used for type 2 diabetes management and weight loss

doi: 10.3390/medicina55060233 179 MarcumZAForsbergCWMooreKPde BoerIHSmithNLBoykoEJet al

Their primary recourse is the BBB, state medical boards, and, in the case of controlled substances, the DEA

Approximately five of the original 19 peptides are expected to remain on the restricted list likely those with more limited safety profiles, higher misuse potential, or closer proximity to existing FDA-approved drug categories

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