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Mitochondria-ros crosstalk in the control of cell death and aging

Obermair A, Kucera E, Mayerhofer K, Speiser P, Seifert M, et al

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The enrolled population was subjects with severe osteogenesis imperfecta, aged 1 to 17 years, 55% male, 84% Caucasian, with a mean lumbar spine BMD of 0.431 gm/cm2, which is 2.7 standard deviations below the mean for age-matched controls (BMD Z-score of -2.7)