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4.1.2 Impact of pyruvate kinase and lactate on macrophage phenotype Pyruvate kinase is a key enzyme in the glycolysis pathway: it catalyzes the dephosphorylation of phosphoenolpyruvate into pyruvate and is responsible for the production of ATP during glycolysis

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Increasing GSH levels through precursor supplementation is a feasible intervention that directly addresses OxS in diabetes

It is likely the expression of TRIMs in cancers is relevant to the development and/or progression of the disease and TRIM expression may have prognostic value for cancer