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Thus, IL-7, as a good factor, could selectively augment immune responses of the redirected CAR-T cells and/or intended effector cells

Measurement of pyridine nucleotides in biological samples using LC-MS/MS

Cross-cancer comparisons reveal that although the SSP serves conserved functions in sustaining one-carbon unit supply and mediating therapeutic resistance across cancer types, the remarkable heterogeneity of its upstream regulatory mechanismsincluding Kras/FGFR3 mutations, MYC-mediated stemness maintenance, and m6A epigenetic modificationsdictates that therapeutic strategies must be precisely tailored