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The isolation window was set at 1.0 m/z and tSIM scans were centered at m/z = 229.1295 (Positive Mode) for hydroimidazolone (MG-H1) and m/z = 380.1122 (Positive Mode) and 378.0966 (Negative Mode) for lactoylglutathione (LGSH)

Moreover, metabolomics has laid a basic foundation to understand the underlying mechanisms and impacted pathways in eye diseases, paving the way for more effective treatments in the future