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BPC-157 has no FDA-approved human therapeutic application, and published human pharmacokinetic data for this exact finished product and dose could not be verified in the peer-reviewed literature reviewed for this article

Other pharmacological options include catechol-O-methyltransferase (COMT) inhibitors like entacapone and opicapone, which extend the half-life of levodopa, do not cross the BBB at all and primarily affect peripheral metabolism, providing no direct action in the brain 59