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Finally, Chimaera 1.15 and Discovery Studio Visualizer version 21.1.0.20298 were used to analyze and visualize the docking postures and interactions between them inside the binding pocket

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After 2 week acute toxicity and cumulative tests in mice, no statistical difference existed between LAAM GSH-CQD group and normal control group in the parameters from complete blood count and serum biochemistry analyses (Supplementary Fig

Whether this negative feedback is mediated directly by the GSL degradation product ITC, due to depletion of glutathione (GSH) [16] which is the sulphur donor in the biosynthesis of GSL [24] or through a sulphur starvation response (discussed later) would require further testing

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