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Sequencing studies of HF cohorts consistently report lower diversity of the gut microbiota and reduced numbers of specific beneficial microbes in patients with HF (Kamo et al., 2017)

Karina Colonetti, ICON plc, United States Updates Copyright 2023 McCaddon and Miller

However, some benefits, such as enhanced detoxification and reduced oxidative stress, may take 4 to 6 weeks to fully manifest

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The relevance of these findings for metabolite transport across the OMM in living cells is unclear and controversially discussed