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validated berberine restrained the growth and induce cell cycle arrest in G0/G1 phase, and apoptosis in NSCLC cells through p38 MAPK-mediated induction of Forkhead box O3a and p53, followed by p21 protein expression

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DCF fluorescence staining demonstrated a slightly greater intracellular ROS accumulation in PQS-treated shCNMT macrophages than in shCNMT macrophages (Supplementary Fig