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Duplication of the TBK-1 associated with NTG patients could be related to autophagy dysfunction and RGCs loss (Tucker et al., 2014

Free Radic Biol Med.2010;48(1):1-15

Author contributions Drafted the manuscript and designed the figures: Jiancheng Mou

Research indicates that following cerebral ischemia, antioxidant enzyme levels significantly de-crease, reactive oxygen species (ROS) production increases, and excessive deposition of amyloid-beta (A) proteins occurs (47)