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Recent research indicated that NOB had antitumor effects on melanoma cells

Of note, the patient was found to have a lice infestation of the scalp and was treated with permethrin 5% cream during hospitalization

The current study has several limitations that need to be addressed in future research

The researchers also found that the cell deaths were promoted by addition of Fe, while inhibited by antioxidants (ferrostatin and Vitamin E) and iron chelator ciclopirox olamine [277]

This polypharmacological approach stands in contrast to conventional chemotherapeutics, which typically target single molecules and are therefore more susceptible to resistance development (Liao et al., 2023)