glutathione gbm6 patient derived xenograft Applications of patient-derived tumor models and tumor organoids Combined inhibition of de novo
Combined inhibition of de novo glutathione and nucleotide biosynthesis is synthetically lethal in glioblastoma ScienceDirect CHCHD2 mediates glioblastoma cell proliferation, mitochondrial metabolism, hypoxia induced invasion, and therapeutic resistance bioRxiv Glutathione peroxidase 4dependent glutathione highconsumption drives acquired platinum chemoresistance in lung cancerderived brain metastasis Liu 2021 Clinical and Translational Medicine Wiley Online Library Telomerase reverse transcriptase induces targetable alterations in glutathione and nucleotide biosynthesis in glioblastomas bioRxiv Patient Derived Tumor Xenograft Models: Toward the Establishment of Precision Cancer Medicine
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