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(PubMed) Pan X, Gong N, Zhao J, et al

SIRT1 activation promotes numerous anti-aging effects including enhanced mitochondrial biogenesis, improved stress resistance, reduced inflammation, and activation of cellular quality control mechanisms that remove damaged proteins and organelles

This study established the core evidence that drives current research interest and it is important to note that this is primarily a preclinical (mouse) evidence base

Severe hypokalaemia (low blood potassium) is rare but can develop in some cases, particularly in severe megaloblastic anaemia or in patients taking certain medications such as diuretics

Pellet was resuspended in glucose-free RPMI medium supplemented with 2-NBDG (Thermo Fisher N13195) at 50 M and incubated for 30 min at 37 C