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The mice had ad libitum access to food and water and were housed under a 12 h light/dark cycle

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To counteract these detrimental effects, cells rely on precise regulatory mechanisms to maintain balanced Ca 2 + levels, ensuring proper cellular function while minimizing the risk of toxicity (Nava et al., 2020

This group only suggests such treatment when IGF-1 deficiency prevails, acting merely as a substitutive therapy, and never to exploit its multiple actions

On the other hand, ginkgo and some flavonoids may inhibit CYP3A4 or Pg-pg, leading to increased drug exposure and an increased risk of toxicity, such as myelosuppression, neuropathy, or hepatotoxicity (203)