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Johnson et al., 2019), limited information is available regarding bioenergetics within the cerebrovasculature, particularly in relation to both FA uptake and fatty acid oxidation (FAO) capabilities within the context of aging and different APOE genotypes, despite the fact that cerebrovascular FAO has been suggested to be an essential process in maintaining its transport functions (Goldstein, 1979)

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L-carnitine supplementation may prevent muscle cramps by ameliorating insufficient cellular energy supplies in skeletal muscles via enhancing the rate of -oxidation of fatty acids, removing short and medium-chain fatty acids, and maintaining glycogen storage [43]