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This product then undergoes further conjugation with either sulphate catalyzed by sulphotransferase to form 6-sulphomelatonin or with glucuronic acid, catalyzed by UDP-glucuronosultransferase to form 6-hydroxymelatonin glucuronide (15)

doi: 10.3390/ijms21061958 50 MagayeRRSaviraFHuaYKellyDJReidCFlynnBet al

DOI: 10.20524/aog.2017.0192

Safety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (SUNBEAM): a multicentre, randomised, minimum 12-month, phase 3 trial