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2022;34(3):408-23 e8

Between 1979 and 2018, there had been 98 cases of D-lactic acidosis documented in humans, nearly all as a result of short bowel-syndrome, and this repeating finding reinforced the concept that D-lactate is a microbial metabolite

In two cases, three mutations were observed and in several patients only one mutation was detected in the heterozygous state

These defect sites can serve as highly active traps that undergo specific strong interactions with Zn 2+ , even forming reversible CClZn coordination structures, thereby achieving charge storage beyond conventional electric double-layer capacitance

These findings suggest that magnesium supplementation may help regenerate pancreatic beta cells and reduce diabetes-related inflammation Rahayu2024Fapohunda2020