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10.1074/jbc.M115.700534 93

Increases in serum ferritin and altered iron metabolism are known to occur with inflammation

doi: 10.1001/jama.2010.1361 225 AshizawaKImaizumiMUsaTTominagaTSeraNHidaAet al

However, high concentrations of free fatty acids released by adipocytes paradoxically induce ferroptosis in myeloma cells (Panaroni 2022)

In particular, they found that, in the absence of BMAL1, NF-B-driven transcription was upregulated by the core circadian protein CLOCK, whereas BMAL1 hindered the CLOCK-induced increase in the activation of NF-B-regulated genes 71