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Among cases of severe hepatotoxicity occurring during VPA therapy, survival has been reported mainly in those patients treated with carnitine [6467], and this approach is likely to be biased

Studies (136, 141) have shown that taurine can prevent and protect testicular abnormalities (e.g., restoring testicular weight, sperm count and T level) caused by DOX and CIS through its antioxidant and anti-apoptotic properties

Neuroinflammation is primarily caused by astrocyte and microglial activation and proliferation, activation, and translocation of transcription factors such as NF-B, and increased production of cytotoxic cytokines such as TNF- and IL-1 (Afshin-Majd et al

The effect of the CPT system on different tissues or organs is complex: the deficiency or over-activation of CPT disrupts the immune homeostasis by causing energy metabolism disorder and inflammatory oxidative damage and therefore contributes to the development of various acute and chronic inflammatory disorders and cancer

He is also named co-inventor on two patents: U.S