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5 Toxicology The main toxic components of ATT are asarones in the volatile oil

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BY4741, a wild-type strain with the genotype Mat a, his31, leu20, met150, ura30 Euroscarf (Frankfurt, Germany), referred to here as wt3 and its derivative strains msn2 , with the genotype MAT a , his31, leu20, met150, ura0, YMR037C::KanMX4 msn4 , with the genotype MAT a, his31 , leu20, met150, ura30, YKL062W::KanMX4 and double mutant msn2msn4 with the genotype MAT a, his31, leu20, met150, ura30, YKR101W::KanMX4, YKL062W::loxP-NatMX-loxP 71

WGM administration improved the general condition of HT rats