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10.1002/sim.1186 27 HouleS

Am J Physiol Gastrointest Liver Physiol

Beyond that, the safety data comes from anecdotal reports in the peptide community

Elevated NNMT activity can slow down energy expenditure and promote fat accumulation (1)

For a deeper understanding, you can explore resources like the National Institutes of Health's information on B Vitamins: Functions and Uses in Medicine