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An update literature review in 2022 (search dates: 06/2013 01/2021) identified 63 studies, 53 of which were added to the evidence base The Panel judged that these were a sufficient evidence base from which to construct the majority of the treatment portion of the guideline and algorithm

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HGF/c-Met pathway in cerebellar development During embryonic development, the progenitor cells localized in the ventricular zone of the cerebellum (also called primary germinal zone), along the IVth ventricle, migrate radially to give rise to Purkinje cells, neurons of the cerebellar nuclei and different types of cerebellar interneurons

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