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Dependence levels measured by the Penn State E-cigarette Dependence Index have also shown to be associated with indices that are indicative of dependence, such as self-perceptions of addiction to e-cigarettes, frequency of e-cigarette use, and time to first e-cigarette use in the morning 15

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SommersTMitsuhashiSSinghPHirschWKatonJBallouSet al

2009;297:L3807

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