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RESULTS The AnglV analog D~Nle-Tyr-Ile-NH-(CH 2 ) 5-CONH2 is more metabolically stable than Norleual (Nle-Tyr-Leu^-(CH 2 -NH 2 f- 4 -His-Pro~Phe (SEQ ID NO: 1) The AnglV-related peptidomimetic Norleual was previously shown to possess, anti- HGF/Met, anti-angiogenic, and anti-cancer activities

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Additionally, this protocol is dependent on supplementing the media with 10% Matrigel and expensive growth factors

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