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Description

The MDSC and neutrophils create arginase, which depletes arginine from the TME

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DNA ligase IV, which plays a vital role in non-homologous end joining (NHEJ), can use NAD+ to get AMP moiety for DNA end ligation

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1 2 J Int Med Res

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Accessed 10/3/2022, Nourbakhsh A, Colbert BM, Nisenbaum E, et al

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